by Clinicalmicrobiology & Infectious Diseases | Aug 1, 2022
Abstract Emergence of antimicrobial resistance worldwide is responsible for alarming situation. There is an urgent need to discover more effective, safer and less toxic antibacterial agents. Medicinal plants are valuable alternative resources for developing novel...
by Clinicalmicrobiology & Infectious Diseases | Aug 1, 2022
Abstract The association of other active drugs or substances with benznidazole (BZ) or nifurtimox (NF) has been stimulated to treat Chagas disease (CD) since these drugs present limitations. As the dog is an excellent model for Chagas disease study and its treatment,...
by Clinicalmicrobiology & Infectious Diseases | Aug 1, 2022
Abstract Acute kidney injury is a common ailment that ensues when the kidney is exposed to different insults, including ischemia/reperfusion (I/R), a disorder detected in cases of septic shock, cardiovascular surgery, and kidney transplantation and in addition it...
by Clinicalmicrobiology & Infectious Diseases | Aug 1, 2022
Abstract This study evaluated the diagnostic performance of the AccuPower® TB&MDR Real-Time PCR (TBMDR®) and AccuPower® XDR-TB Real-Time PCR Kit-A (XDRA®) to detect multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) in comparison...
by Clinicalmicrobiology & Infectious Diseases | Aug 1, 2022
Abstract The ethnic communities of Darjeeling hills still depend on plant-derived resources for disease cure. Although folk medicine is perhaps the most popular in tribal area, it has not been explored fully till now. In recent years, bioactive plant constituents have...
by Clinicalmicrobiology & Infectious Diseases | Jul 27, 2022
Abstract Background: Infection control is one of the major global public health problems due to rapid emergence of Anti-Microbial Resistance (AMR). Intensive Care Units (ICUs) are considered as epicenter of development of AMR. Management of diseases with various...
by Clinicalmicrobiology & Infectious Diseases | Feb 10, 2022
Abstract Contamination is the presence of unwanted material on the desirable surface. Bio-contamination is the undesirable presence of the microbes such as viruses, bacteria, and fungi or end products such as endotoxin and mycotoxins inside a medium and leads to a...
by Clinicalmicrobiology & Infectious Diseases | Feb 10, 2022
Abstract Objectives: This study aimed to investigate an outbreak of a non-malaria, undifferentiated febrile illness, among internally displaced persons (IDPs) living in humanitarian camps in North Darfur, Sudan, in 2019. Methods: An investigation team was deployed to...
by Clinicalmicrobiology & Infectious Diseases | Feb 10, 2022
Abstract Giardia intestinalis continues to be one of the most encountered parasitic diseases around the world. Although more frequently detected in developing countries, Giardia infections nonetheless pose significant public health problems in developed countries as...
by Clinicalmicrobiology & Infectious Diseases | Feb 10, 2022
Abstract In December 2020, the Ministry of Health in Israel approved the Pfizer-BioNTech mRNA vaccine (BNT162b2) for prevention of COVID-19 disease shortly after the Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for it. Shortly...
by Clinicalmicrobiology & Infectious Diseases | Sep 14, 2021
Abstract The Plasmodium falciparum (P. falciparum) reticulocyte binding protein homologue 5 (PfRH5) has recently shown great promise to be developed as a vaccine candidate to prevent blood stage malaria. Historically observed difference in the immunogenicity and...
by Clinicalmicrobiology & Infectious Diseases | Sep 14, 2021
Abstract Tobacco addiction remains one of the largest preventable causes of disease and death worldwide. Recently, the use of nicotine e-cigarettes has dramatically increased among many populations, including youth. These devastating trends have been paralleled by the...
by Clinicalmicrobiology & Infectious Diseases | Sep 14, 2021
Abstract The novel coronavirus pandemic is an ongoing challenge faced by the public and health care systems around the globe. Majority of information and evidence gathered so far has been derived from data and studies in adult populations. Crucial information...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
Abstract Ethnopharmacological relevance: Plant materials are used worldwide as complementary and alternative therapeutics for the treatment of various illnesses. In Ethiopia, folk medicines are utilized across a wide range of cultures and settings. Ethiopia has...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
Abstract Backgound: The immune system is profoundly affected by uremia. End stage kidney disease (ESKD) patients may be more vulnerable to infections and may have suboptimal response to vaccination. For the SARS-COV-2 (COVID-19), patients with ESKD are at increased...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
Abstract Cancer is currently a major threat to public health, being among the principal causes of death to the global population. With carcinogenesis mechanisms, cancer invasion, and metastasis remaining blurred, cancer diagnosis and novel drug delivery approaches...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
Abstract Since the first described case in December 2019, the coronavirus disease 2019 (COVID-19) has been one of the most significant challenges of our time. The clinical spectrum ranges from asymptomatic to critical forms with acute respiratory distress syndrome and...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
ABSTRACT Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spurred a global health crisis.The safety and supply of blood during this pandemic has been a concern of different blood banks and transfusion services as it is expected to reduce the blood...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
Abstract Amyotrophic Lateral Sclerosis(ALS) remains a terminal disease without an established etiology for the majority of patients. The dominant theory of ALS before the 1970’s was the presence of a poison. One of the primary means of treating patients with a toxic...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
Abstract Burkholderia gladioli was described as a plant pathogen, and it is a rare cause of infection in humans that is primarily associated with human pulmonary infections, such as chronic granulomatous disease and cystic fibrosis. The neonatal respiratory system is...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
Abstract Background: Hypoxic microenvironment is a common feature of solid tumors, which leads to the promotion of cancer. The transcription factor, HIF-1α, expressed under hypoxic conditions stimulates tumor angiogenesis, favoring HIF-1α as a promising anticancer...
by Clinicalmicrobiology & Infectious Diseases | Jun 15, 2021
Abstract Mycobacterium tuberculosis (Mtb) is a bacterium that is difficult to defeat. It is one of the main causes of morbidity and mortality and is the primary cause of Tuberculosis (TB). Elective curative methodologies are increasingly securing drug hindrance for TB...
by Clinicalmicrobiology & Infectious Diseases | Apr 30, 2021
Abstract With the advancement of the Covid-19 pandemic, this work aims to find molecules that can inhibit the attraction between the Spike proteins of the SARS-COV-2 virus and human ACE2. The results of molecular docking positioned four molecules at the interaction...
by Clinicalmicrobiology & Infectious Diseases | Apr 29, 2021
Abstract In the era of coronavirus disease 2019 (COVID-19), the management of cardiac implantable electronic devices infections with concomitant viral infection has not been completely defined yet. In this explorable context, we report the first experience of a...
by Clinicalmicrobiology & Infectious Diseases | Apr 6, 2021
Abstract Illicit drug use can cause a variety of effects including alterations in the immune system. The goal of our study was to evaluate the impact of illicit drug use on inflammation and oxydative stress status in people living with HIV (PLHIV) or not. Circulating...
by Clinicalmicrobiology & Infectious Diseases | Feb 18, 2021
Abstract The bioconvection of gravitactic microorganisms, through linear analysis and numerical simulation is presented. Using the basic state as initial condition for both microorganisms and streamlines, the critical Rayleigh number and the bioconvection are...
by Clinicalmicrobiology & Infectious Diseases | Feb 16, 2021
Abstrat Background: the search for predictors of malaria outcome is essential, because a successful, inexpensive, fast and easy to measure predictive test, with minimal infrastructure requirements or specialized training, can be used in malaria endemic environments to...
by Clinicalmicrobiology & Infectious Diseases | Dec 17, 2020
Abstract Candida-associated gastric ulcer occurs not only in debilitated but healthy individuals. Though had been reported to demonstrate nothing but nonspecific endoscopic features, it occasionally exhibits a typical finding I designated a candidarium. The natural...
by Clinicalmicrobiology & Infectious Diseases | Dec 17, 2020
Abstract Cancer is one of the leading causes of death in the world. Traditional cancer treatments, including surgery, chemotherapy and radiation therapy, have demonstrated very limited efficacy for patients with late-stage disease. Cancer immunotherapy has shown great...
by Clinicalmicrobiology & Infectious Diseases | Dec 17, 2020
Abstract Since the outbreak of Coronavirus Disease-19 (COVID-19) infection in December 2019 in Wuhan, the capital Hubei province, central of China, more than 4 million people have contracted the virus worldwide. Despite the imposed precautions, coronavirus disease-19...
by Clinicalmicrobiology & Infectious Diseases | Dec 16, 2020
Abstract In aqueous media, phospholipids are self-assembled into lipid bilayers. In biological membranes, proteins are hidden in lipid bilayers. It is well known that each protein and lipid have distinct characters. From the structures and functions study, it is...
by Clinicalmicrobiology & Infectious Diseases | Dec 16, 2020
Abstract Purpose: The purpose of this study was to compare the efficacy and safety of a proposed bevacizumab biosimilar to those of the reference product in patients with metastatic colorectal cancer (mCRC). Methods: This Phase III, multicenter, randomized,...
by Clinicalmicrobiology & Infectious Diseases | Dec 16, 2020
Abstract Preventing bacterial infections from becoming the leading cause of death by the year 2050 requires the development of novel, infection-control strategies, building heavily on biomaterials science, including nanotechnology. Pre-clinical (animal) studies are...
by Clinicalmicrobiology & Infectious Diseases | Dec 16, 2020
Abstract Objectives: This study analyzed Protease-PR and Reverse Transcriptase-RT HIV-1 genomic information entropy metrics among patients under antiretroviral virologic failure, according to the numbers of virologic failures or resistance mutations. Methods: For this...
by Clinicalmicrobiology & Infectious Diseases | Dec 16, 2020
Abstract The advent of drug-eluting stents and drug-coated balloons have significantly improved the clinical outcome of patients with vascular occlusions. However, ischemic vascular disease remains the most common cause of death worldwide. Although the next generation...
by Clinicalmicrobiology & Infectious Diseases | Dec 16, 2020
Abstract Tuberculosis has attracted increased attention worldwide due to its high morality and its resistance to treatment with traditional antibacterial drugs. The L,D-transpeptidase LdtMt2 confers resistance to traditional b-lactams and is considered a target for...
by Clinicalmicrobiology & Infectious Diseases | Dec 16, 2020
Abstract In dairy cattle, mastitis is a disease of the mammary gland caused by pathogens, such as bacteria, viruses, fungi, and algae. Mastitis causes economic losses to dairy farms, as well as public health concerns. The reproductive efficiency of commercial dairy...
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